flowDLS - Real-time particle size measurement

flowDLS is an inline technology for real-time particle size measurement in continuous production processes, developed by Fraunhofer IMM.

 

The solution is based on dynamic light scattering (DLS) and was specifically designed for use in material flow—without sampling and without interrupting the process.

Strategic Added Value:

  • Real-time process control
    flowDLS provides continuous measurement data directly from the running process. This allows deviations to be detected immediately and process parameters to be adjusted on the spot.
  • Accelerated Development & Scale-up
    Immediate feedback significantly shortens development cycles. The transition from laboratory to production scale is simplified and validated using data.
  • Inline quality assurance (PAT-ready)
    flowDLS supports modern Quality-by-Design and Process Analytical Technology strategies. Continuous monitoring enhances reproducibility, product safety, and regulatory transparency.
  • Economic efficiency
    Fewer offline analyses, lower scrap rates, and optimized process control result in measurable cost savings and higher plant productivity.

Target Markets & Applications

  • Pharmaceutical Nanoparticles and Drug Delivery Systems
  • Lipid Nanoparticles and Functional Dispersions
  • Chemical and Materials Science Synthesis Processes
  • Continuous Microreactor Technologies

 

flowDLS addresses the growing need for data-driven process control in high-value industries. The technology enables the transition from batch-based quality inspection to true inline process intelligence.