From batch to flow processing
High selectivities and yields play a particularly important role in the individual synthesis steps of the mostly multi-stage synthesis of active pharmaceutical ingredients. Furthermore, the implementation of „Green Chemistry” and “Green Engineering” is of central importance for the global pharmaceutical companies in order to reach economic and environmental sustainability in the pharmaceutical industry. The twelve observed "Green Chemistry" principles include amongst others waste prevention, the efficient use of raw materials and the minimization of energy use as well as the implementation of a real-time process monitoring. The traditional and established manufacturing processes of pharmaceuticals are mainly based on batch processing. The quality control takes place via laboratory tests drawn from process samples. Innovations in the development of pharmaceuticals are expected from the product and process development, process analysis and process control.
„We will help you to exploit the full potential of your chemical processes”
Our approach to the necessary innovations is based on the following methods and technologies:
- Transfer of batch processes into continuous processing,
- use of microreactors and flow chemistry in synthesis,
- integration of inline sensors as a basis for effective process control.